Members:

Soichi Nagao: Lab for Motor Learning Control, RIKEN BSI
Yutaka Hirata: Dept. of Computer Science, College of Engineering, Chubu University
Tadashi Yamazaki: RIKEN BSI-TOYOTA Collaboration Center, RIKEN BSI
Shinji Kakei: Tokyo Metropolitan Institute for Neuroscience
Shiro Usui: Neuroinformatics Japan Center, RIKEN BSI

Jan 21--26, 2012.

PLoS ONE Published January 19, 2012 to January 25, 2012

Pre and Post Synaptic NMDA Effects Targeting Purkinje Cells in the Mouse Cerebellar Cortex
Etienne Lonchamp, Frédéric Gambino, Jean Luc Dupont, Frédéric Doussau, Antoine Valera, Bernard Poulain, Jean-Louis Bossu
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030180

Nature contents: 26 January 2012

Purkinje neuron synchrony elicits time-locked spiking in the cerebellar nuclei
Abigail L. Person and Indira M. Raman
Through a combination of intrinsic and synaptic properties,
synchronous activation of a small number of Purkinje cells can set
the spike timing of target neurons in the cerebellar nuclei.
http://www.nature.com/nature/journal/v481/n7382/full/nature10732.html

J. Neurosci. Table of Contents for 25 January 2012; Vol. 32, No. 4

Cav2.1 in Cerebellar Purkinje Cells Regulates Competitive Excitatory Synaptic Wiring, Cell Survival, and Cerebellar Biochemical Compartmentalization
Taisuke Miyazaki, Miwako Yamasaki, Kouichi Hashimoto, Maya Yamazaki, Manabu Abe, Hiroshi Usui, Masanobu Kano, Kenji Sakimura, and Masahiko Watanabe
J. Neurosci. 2012;32 1311-1328
http://www.jneurosci.org/cgi/content/abstract/32/4/1311?etoc

Jan 14--20, 2012.

Neuroscience Letters, Vol. 508, Iss. 1, 2012

12) Volumetric variation in subregions of the cerebellum correlates with working memory performance
Pages 47-51
Hui Ding, Wen Qin, Tianzi Jiang, Yunting Zhang, Chunshui Yu
http://www.sciencedirect.com/science/article/pii/S0304394011016168

Neuropharmacology, Vol. 62, Iss. 2, 2012

30) Receptor-mediated modulation of activity-dependent adenosine release in rat cerebellum
Original Research Article,
Pages 815-824
Boris P. Klyuch, Nicholas Dale, Mark J. Wall
http://www.sciencedirect.com/science/article/pii/S0028390811004011

Cell Volume 148 Issue 1 and 2 Annotated Table of Contents

Mutation of a U2 snRNA Gene Causes Global Disruption of Alternative Splicing and Neurodegeneration
Y. Jia, J.C. Mu, and S.L. Ackerman
http://www.cell.com/abstract/S0092-8674%2811%2901506-6
   Expression of U2 snRNA genes, present in multiple copies in the genome, is surprisingly not ubiquitous, but rather individual genes show tissue-specific expression. Mutation in a single U2 snRNA gene disrupts specific alternative splicing events in the cerebellum and causes neurodegeneration.

European Journal of Neuroscience Vol. 35 Issue 2

AMPA receptor modulation by cornichon-2 dictated by transmembrane AMPA receptor regulatory protein isoform (pages 182–194)
Martin B. Gill, Akihiko S. Kato, He Wang and David S. Bredt
Article first published online: 30 DEC 2011 | DOI: 10.1111/j.1460-9568.2011.07948.x
http://onlinelibrary.wiley.com/doi/10.1111/j.1460-9568.2011.07948.x/abstract
Transmembrane AMPA receptor regulatory proteins (TARPs) are auxiliary subunits that modulate AMPA receptor trafficking, gating and pharmacology throughout the brain. Why cornichon-2 (CNIH-2), another AMPA receptor-associated protein, modulates AMPA receptor gating and pharmacology in hippocampal neurons but not cerebellar granule neurons remains unresolved.

European Journal of Neuroscience Vol. 35 Issue 1

Cerebellar long-term depression requires dephosphorylation of TARP in Purkinje cells
Toshihiro Nomura, Wataru Kakegawa, Shinji Matsuda, Kazuhisa Kohda, Jun Nishiyama, Takao Takahashi and Michisuke Yuzaki
Article first published online: 12 JAN 2012 | DOI: 10.1111/j.1460-9568.2011.07963.x
http://onlinelibrary.wiley.com/doi/10.1111/j.1460-9568.2011.07963.x/abstract
Cerebellar long-term depression (LTD) at parallel fiber (PF) – Purkinje cell synapses is thought to play an essential role in certain forms of motor learning. Like hippocampal LTD, cerebellar LTD is mediated by the endocytosis of AMPA ([alpha]-amino-3-hydroxyl-5- methyl-4-isoxazole-propionate) receptors at postsynaptic sites.
 

Dec 26, 2011 -- Jan 13, 2012.

Neuron Volume 73 Issue 1

Identification of an Inhibitory Circuit that Regulates Cerebellar Golgi Cell Activity
Court Hull, Wade G. Regehr
http://www.cell.com/neuron/abstract/S0896-6273%2811%2900994-9
Golgi cells are a crucial source of inhibition in the cerebellum. It was previously thought that Golgi cell activity was regulated by inhibition from molecular layer interneurons (MLIs). Hull and Regehr overturn this view by revealing instead that Golgi cells inhibit each other.

Neuroscience, Vol. 201, 2012

4) Climbing fiber activity reduces 14-3-3-θ regulated GABAAreceptor phosphorylation in cerebellar Purkinje cells
Original Research Article,
Pages 34-45
Z. Qian, M. Micorescu, V. Yakhnitsa, N.H. Barmack
http://www.sciencedirect.com/science/article/pii/S0306452211012887

NeuroImage, Vol. 59, Iss. 3, 2012

82) Biological motion processing: The left cerebellum communicates with the right superior temporal sulcus
Original Research Article,
Pages 2824-2830
Arseny A. Sokolov, Michael Erb, Alireza Gharabaghi, Wolfgang Grodd, Marcos S. Tatagiba, Marina A. Pavlova
http://www.sciencedirect.com/science/article/pii/S1053811911009384

PLoS ONE Published December 28, 2011 to January 04, 2012

Cerebellar Globular Cells Receive Monoaminergic Excitation and Monosynaptic Inhibition from Purkinje Cells
Moritoshi Hirono, Fumihito Saitow, Moeko Kudo, Hidenori Suzuki, Yuchio Yanagawa, Masahisa Yamada, Soichi Nagao, Shiro Konishi, Kunihiko Obata
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0029663

European Journal of Neuroscience Content Alert: 35, 1 (January 2012)

P/Q-type and T-type calcium channels, but not type 3 transient receptor potential cation channels, are involved in inhibition of dendritic growth after chronic metabotropic glutamate receptor type 1 and protein kinase C activation in cerebellar Purkinje cells (pages 20–33)
Olivia S. Gugger, Jana Hartmann, Lutz Birnbaumer and Josef P. Kapfhammer
Article first published online: 22 DEC 2011 | DOI: 10.1111/j.1460-9568.2011.07942.x
http://onlinelibrary.wiley.com/doi/10.1111/j.1460-9568.2011.07942.x/abstract

NeuroReport - January 25, 2012 - Volume 23 - Issue 2
   
c-Jun induction is independent of early growth response factor during cerebellar granule neuron apoptosis
Song, Bin; Xie, Bo; Wang, Chong; Li, Mingtao
http://journals.lww.com/neuroreport/Abstract/2012/01250/c_Jun_induction_is_independent_of_early_growth.3.aspx

Neuroscience Letters Volume 506, Issue 2, Pages 175-350, 11 January 2012

22) Cntnap2 expression in the cerebellum ofFoxp2(R552H) mice, with a mutation related to speech-language disorder
Pages 277-280
Eriko Fujita, Yuko Tanabe, Mariko Y. Momoi, Takashi Momoi

http://www.sciencedirect.com/science/article/pii/S0304394011015448

 

Dec 2-Dec 25, 2011.

Nature Neuroscience Contents: January 2012 Volume 15 Number 1, pp 1 - 170

How the 'slow' Ca2+ buffer parvalbumin affects transmitter release in
nanodomain-coupling regimes     pp20 - 22
Emmanuel Eggermann and Peter Jonas
doi:10.1038/nn.3002
The authors conduct direct measurements of parvalbumin concentration
and paired recordings in rodent hippocampus and cerebellum and show
that parvalbumin affects synaptic dynamics, exerting Ca2+-buffering
effects only when expressed at high levels.
http://www.nature.com/neuro/journal/v15/n1/abs/nn.3002.html

J Neurophysiol Table of Contents for January 2012; Vol. 107, No. 1

Cerebellar regions involved in adaptation to force field and visuomotor perturbation
    Opher Donchin, Kasja Rabe, Jörn Diedrichsen, Níall Lally, Beate Schoch, Elke Ruth Gizewski, and Dagmar Timmann
    J Neurophysiol 2012;107 134-147
    http://jn.physiology.org/cgi/content/abstract/107/1/134

A late phase of LTD in cultured cerebellar Purkinje cells requires persistent dynamin-mediated endocytosis
    David J. Linden
    J Neurophysiol 2012;107 448-454
    http://jn.physiology.org/cgi/content/abstract/107/1/448

Brain Research Volume 1432, Pages 1-122, 13 January 2012

5) Differential effects of ethanol on c-jun N-terminal kinase, 14-3-3 proteins, and Bax in postnatal day 4 and postnatal day 7 rat cerebellum
Original Research Article,
Pages 15-27
Marieta Barrow Heaton, Michael Paiva, Stacey Kubovic, Alexandra Kotler, Jonathan Rogozinski, Eric Swanson, Vladimir Madorsky, Michelle Posados
http://www.sciencedirect.com/science/article/pii/S0006899311020373
   
European Journal of Neuroscience Volume 34, Issue 12 Pages 1887 - 2066, December 2011

Exposure to hypergravity during specific developmental periods differentially affects metabolism and vestibular reactions in adult C57BL /6j mice (pages 2024–2034)
Mickael Bojados and Marc Jamon
Article first published online: 29 NOV 2011 | DOI: 10.1111/j.1460-9568.2011.07919.x
http://onlinelibrary.wiley.com/doi/10.1111/j.1460-9568.2011.07919.x/abstract

The development of the posturo-motor control of movement is conditioned by Earth’s gravity. Missing or altered gravity during the critical periods of development delays development and induces durable changes in the vestibular, cerebellar, or muscular structures, but these are not consistently mirrored at a functional level.

J. Neurosci. Table of Contents for 14 December 2011; Vol. 31, No. 50

Activity-dependent Increases in Local Oxygen Consumption Correlate with Postsynaptic Currents in the Mouse Cerebellum In Vivo
Claus Mathiesen, Kirsten Caesar, Kirsten Thomsen, Tycho M. Hoogland, Brent, M. Witgen, Alexey Brazhe, and Martin Lauritzen
J. Neurosci. 2011;31 18327-18337
http://www.jneurosci.org/cgi/content/abstract/31/50/18327?etoc

Brain Research Volume 1427, Pages 1-88, 3 January 2012

8) Selective loss of AMPA receptor subunits at inhibitory neuron synapses in the cerebellum of the ataxic stargazer mouse
Original Research Article,
Pages 54-64
Olga Shevtsova, Beulah Leitch
http://www.sciencedirect.com/science/article/pii/S0006899311019275

NeuroImage Volume 59, Issue 2, Pages 881-1978, 16 January 2012

78) Functional topography of the cerebellum for motor and cognitive tasks: An fMRI study
Original Research Article,
Pages 1560-1570
Catherine J. Stoodley, Eve M. Valera, Jeremy D. Schmahmann
http://www.sciencedirect.com/science/article/pii/S1053811911009827

88) Specific cerebellar regions are related to force amplitude and rate of force development
Original Research Article,
Pages 1647-1656
M.B. Spraker, D.M. Corcos, A.S. Kurani, J. Prodoehl, S.P. Swinnen, D.E. Vaillancourt
http://www.sciencedirect.com/science/article/pii/S1053811911010652

Nov. 25-Dec 1, 2011.

NeuroReport - January 4, 2012 - Volume 23 - Issue 1
   
ELKS1 and Ca2+ channel subunit β4 interact and colocalize at cerebellar synapses
Billings, Sara E.; Clarke, Gwenaëlle L.; Nishimune, Hiroshi
http://journals.lww.com/neuroreport/Abstract/2012/01040/ELKS1_and_Ca2__channel_subunit__4_interact_and.11.aspx

European Journal of Neuroscience Volume 34, Issue 11 Pages 1711 - 1885, December 2011

Sensorimotor integration for speech motor learning involves the inferior parietal cortex (pages 1817–1822)
Mamie Shum, Douglas M. Shiller, Shari R. Baum and Vincent L. Gracco
Article first published online: 18 NOV 2011 | DOI: 10.1111/j.1460-9568.2011.07889.x
Sensorimotor integration is important for motor learning. The inferior parietal lobe, through its connections with the frontal lobe and cerebellum, has been associated with multisensory integration and sensorimotor adaptation for motor behaviors other than speech.
http://onlinelibrary.wiley.com/doi/10.1111/j.1460-9568.2011.07889.x/abstract